São Paulo (Brazil) is 2.2 times larger than Cuba.
Area: 110,860 km2 World Factbook
Population: 11,047,251 (July 2014) World Factbook
Cuba, officially the Republic of Cuba, is an island country in the Caribbean. The nation of Cuba comprises the main island of Cuba, the Isla de la Juventud, and several archipelagos. Havana is the capital of Cuba and its largest city. The second largest city is Santiago de Cuba. Wikipedia
São Paulo is a state in Brazil. It is the major industrial and economic powerhouse of the Brazilian economy. Named after Saint Paul, São Paulo has the largest population, industrial complex, and economic production in the country. It is the richest state in Brazil. Wikipedia