Kentucky (USA) is 840 times larger than San Francisco.
Kentucky, officially the Commonwealth of Kentucky, is a state located in the east south-central region of the United States. Kentucky is one of four U.S. states constituted as a commonwealth. Originally a part of Virginia, in 1792 Kentucky became the 15th state to join the Union. Wikipedia
Area: 122 km2 calculated
San Francisco, officially the City and County of San Francisco, is the cultural center and a leading financial hub of the San Francisco Bay Area and Northern California. Wikipedia