Louisiana (USA) is 405 times larger than Durham, North Carolina.
Louisiana is a state located in the southern region of the United States. Louisiana is the 31st most extensive and the 25th most populous of the 50 United States. Its capital is Baton Rouge and largest city is New Orleans. Louisiana is the only state in the U.S. Wikipedia
Area: 276 km2 calculated
Durham is a city in the U.S. state of North Carolina. It is the county seat of Durham County, though portions also extend into Wake County in the east and Orange County in the west. Wikipedia