Detroit is 871 times larger than Vatican.
Area: 0 km2 World Factbook
Population: 842 (July 2014) World Factbook
Vatican City, officially Vatican City State, is one of the last six remaining absolute monarchies whose territory consists of a walled enclave within the city of Rome. It has an area of approximately 44 hectares, and a population of around 840. Wikipedia
Area: 383 km2 calculated
Detroit is the most populous city in the U.S. state of Michigan and the largest city on the United States-Canada border. It is the seat of Wayne County, the most populous county in the state. Wikipedia