Knoxville, Tennessee is 2.3 times larger than Gainesville, Florida.
Area: 145 km2 calculated
Gainesville is the county seat and largest city in Alachua County, Florida, and the principal city of the Gainesville, Florida Metropolitan Statistical Area. The population of Gainesville in the 2010 United States Census was 124,354. Wikipedia
Area: 332 km2 calculated
Knoxville is a city in the U.S. state of Tennessee, and the county seat of Knox County. The city had a population of 178,874 as of the 2010 census and an estimated population of 183,270 in 2013, making it the state's third largest city. Wikipedia