Des Moines, Iowa is 2.2 times larger than South Bend, Indiana.
Area: 235 km2 calculated
Des Moines is the capital and the most populous city in the U.S. state of Iowa. It is also the county seat of Polk County. A small portion of the city extends into Warren County. It was incorporated on September 22, 1851, as Fort Des Moines which was shortened to "Des Moines" in 1857. Wikipedia
Area: 109 km2 calculated
The city of South Bend is the county seat of St. Joseph County, Indiana, United States, on the St. Joseph River near its southernmost bend, from which it derives its name. Wikipedia