Baltimore is 74% larger than San Francisco.
Area: 212 km2 calculated
Baltimore is the largest city in the U.S. state of Maryland and the 26th-most populous city in the country. It is located in the central area of the state along the tidal portion of the Patapsco River, an arm of the Chesapeake Bay. Wikipedia
Area: 122 km2 calculated
San Francisco, officially the City and County of San Francisco, is the cultural center and a leading financial hub of the San Francisco Bay Area and Northern California. Wikipedia