Columbia, South Carolina is 2.2 times larger than Columbia, Missouri.
Area: 161 km2 calculated
Columbia is a city of 115,276 people in Missouri, a state of the American Midwest. Founded in 1818 as the county seat of Boone County and home to the University of Missouri, it is the principal municipality of the Columbia Metropolitan Area, the fourth most populous urban area in Missouri. Wikipedia
Area: 348 km2 calculated
Columbia is the state capital and largest city in the State of South Carolina. The population was 129,272 according to the 2010 census. The 2013 United States Census estimates put the city at 133,358. Wikipedia