Albuquerque, New Mexico is 4.1 times larger than San Francisco.
Area: 501 km2 calculated
Albuquerque is the most populous city in the U.S. state of New Mexico. It is the county seat of Bernalillo County, and it is situated in the central part of the state, straddling the Rio Grande. Wikipedia
Area: 122 km2 calculated
San Francisco, officially the City and County of San Francisco, is the cultural center and a leading financial hub of the San Francisco Bay Area and Northern California. Wikipedia