San Jose, California is 12 times larger than Lowell, Massachusetts.
Area: 38 km2 calculated
Lowell is a city in Middlesex County, Massachusetts, in the United States. With an estimated population of 108,522, it is the fourth-largest city in Massachuetts, after Boston, Worcester, and Springfield, and the second-largest in what the U.S. Census Bureau defines as Boston's metropolitan area. Wikipedia
Area: 470 km2 calculated
San Jose is the third-largest city in California, the tenth-largest in the United States, and the county seat of Santa Clara County. San Jose is the largest city within Silicon Valley, which is a major component of the greater Bay Area. It is the largest city in Northern California. Wikipedia