Pittsburgh is 58% larger than Rochester, New York.
Area: 153 km2 calculated
Pittsburgh is the seat of Allegheny County and with a population of 305,841 is the second-largest city in the U.S. state of Pennsylvania. With a metropolitan CSA population of 2,659,937, it is the largest in both the Ohio Valley and Appalachia and the 20th-largest in the U.S. Wikipedia
Area: 96 km2 calculated
Rochester is a city in Monroe County, New York, south of Lake Ontario in the United States. Known as the World's Image Center, it was also once known as the Flour City, and more recently as The Flower City, annually hosting the Lilac Festival. It is the county seat for Monroe County. Wikipedia